FunGeST latest publications
Pharmacogenomic Characterization of a Large Cohort of Patient-Derived Cell Lines Identifies Therapeutic Strategies for Pleural Mesothelioma. Assié, J.-B., Meiller, C., Stern, E., Lasvergnas, J., Arnould, M., Pan, L., Montagne, F., Sequeiros, R., Al Zreibi, C., Del Nery, E., Genovesio, A., Lantuejoul, S., Le Pimpec-Barthes, F., Zucman-Rossi, J., Jaurand, M.-C., Blanquart, C., Wald, O., Jean, D., 2026. Cancer Res 86, 196–212.
Targeting ATR to overcome cisplatin resistance in hepatoblastoma. Morel-Ribeiro, P., Cornet, M., Pilet, J., Asif-Laidin, A., Schaeffer, S., Bourdeaux, D., Cavaignac, M., Hirsch, T.Z., Pire, A., Imbeaud, S., Morcrette, G., Zhu, C., Cadiou, M., Marmier, S., Elamouri, Z., Aerts, I., Chardot, C., Sarnacki, S., Taque, S., Guettier, C., Ferlicot, S., Mussini, C., Branchereau, S., Fresneau, B., Ronot, M., Desdouets, C., Nault, J.-C., Zucman-Rossi, J., Rebouissou, S., 2025. Journal of Hepatology.
HPV Genomic Status in Early Cervical Cancer and Its Prognosis Association. Doghman, I., Montero-Macías, R., Malassigné, V., Puech, J., Imbeaud, S., Le Frère-Belda, M.-A., Rigolet, P., Boulhic, M., Stankovic, I., Angeles, M.A., Mery, E., Bats, A.-S., Mathevet, P., Lécuru, F., Veyer, D., Péré, H., 2025. Journal of Medical Virology 97, e70720.
Mutational signature, cancer driver genes mutations and transcriptomic subgroups predict hepatoblastoma survival. Pire, A., Hirsch, T.Z., Morcrette, G., Imbeaud, S., Gupta, B., Pilet, J., Cornet, M., Fabre, M., Guettier, C., Branchereau, S., Brugières, L., Guerin, F., Laithier, V., Coze, C., Nagae, G., Hiyama, E., Laurent-Puig, P., Rebouissou, S., Sarnacki, S., Chardot, C., Capito, C., Faure-Conter, C., Aerts, I., Taque, S., Fresneau, B., Zucman-Rossi, J., 2024. European Journal of Cancer 200, 113583.
Single-cell multiomics reveals the interplay of clonal evolution and cellular plasticity in hepatoblastoma. Roehrig, A., Hirsch, T.Z., Pire, A., Morcrette, G., Gupta, B., Marcaillou, C., Imbeaud, S., Chardot, C., Gonzales, E., Jacquemin, E., Sekiguchi, M., Takita, J., Nagae, G., Hiyama, E., Guérin, F., Fabre, M., Aerts, I., Taque, S., Laithier, V., Branchereau, S., Guettier, C., Brugières, L., Fresneau, B., Zucman-Rossi, J., Letouzé, E., 2024. Nat Commun 15, 3031.
Preneoplastic liver colonization by 11p15.5 altered mosaic cells in young children with hepatoblastoma. Pilet, J., Hirsch, T.Z., Gupta, B., Roehrig, A., Morcrette, G., Pire, A., Letouzé, E., Fresneau, B., Taque, S., Brugières, L., Branchereau, S., Chardot, C., Aerts, I., Sarnacki, S., Fabre, M., Guettier, C., Rebouissou, S., Zucman-Rossi, J., 2023. Nat Commun 14, 7122.
Common genetic variation in alcohol-related hepatocellular carcinoma: a case-control genome-wide association study. Trépo, E., Caruso, S., Yang, J., Imbeaud, S., Couchy, G., Bayard, Q., Letouzé, E., Ganne-Carrié, N., Moreno, C., Oussalah, A., Féray, C., Blanc, J.F., Clément, B., Hillon, P., Boursier, J., Paradis, V., Calderaro, J., Gnemmi, V., Nault, J.-C., Guéant, J.-L., Devière, J., Archambeaud, I., Vitellius, C., Turlin, B., Bronowicki, J.-P., Gustot, T., Sutton, A., Meiller, C., Cao, Q., Hirsch, T.Z., Rebouissou, S., Degré, D., Otero Sanchez, L., Rosewick, N., Quertinmont, E., Desille-Dugast, M., François-Vié, M., Moins, C., Leteurtre, E., Lassailly, G., Ningarhari, M., Boleslawski, E., Cottet, V., Ziol, M., Nahon, P., Zucman-Rossi, J., 2022. The Lancet Oncology 23, 161–171.
Integrated Genomic Analysis Identifies Driver Genes and Cisplatin-Resistant Progenitor Phenotype in Pediatric Liver Cancer. Hirsch, T.Z., Pilet, J., Morcrette, G., Roehrig, A., Monteiro, B.J.E., Molina, L., Bayard, Q., Trépo, E., Meunier, L., Caruso, S., Renault, V., Deleuze, J.-F., Fresneau, B., Chardot, C., Gonzales, E., Jacquemin, E., Guerin, F., Fabre, M., Aerts, I., Taque, S., Laithier, V., Branchereau, S., Guettier, C., Brugières, L., Rebouissou, S., Letouzé, E., Zucman-Rossi, J., 2021. Cancer Discov 11, 2524–2543.